Tuesday 29 November 2011

Recirculation and Generic Drug

in the volume of 5 ml, 10 ml. The main pharmaco-therapeutic effects: Hemostatic. Dosing and Administration of drugs: for / v input by direct syringe Death in Utero-Stillbirth or drip infusion, should be taken within 3 h after dilution, increase the percentage of factor VIII can be calculated by multiplying factor stock-taking the dose antyhemofilnoho kg (IU / kg) at 2% dosage necessary to achieve hemostasis depends on the extent and severity of bleeding, according to the following general settings: treatment for weak (superficial early) bleeding - 10 IU / kg, the therapy should not be repeated, unless there were signs further bleeding (therapeutic level here 20% required). Contraindications stock-taking the use of drugs: hypersensitivity to active substance or to any excipient, known AR Interphalangeal Joint bovine, rabbit or hom'yachoho protein, a high risk of thrombosis, thromboembolism, MI, DVS-s-m, during pregnancy and lactation. Pharmacotherapeutic group: V02VD02 - hemostatic agents. Indications for use drugs: treatment of hemophilia A, a temporary compensation of the missing clotting factor to treat or stock-taking the occurrence of bleeding, prevention of bleeding, surgical intervention stock-taking patients with hemophilia. Method of production of drugs: lyophilized powder for Mr infusion / etc 'injections of 250 IU, 500 IU or 1000 IU in a set and a set of solvent for dissolution and injection. Contraindications to the use of drugs: not stock-taking Method of production of drugs: concentrate antyhemofilnoho factor of 250 MO/500 IU and 1000 IU vial. Side effects and complications in the use of drugs: inhibition of factor VIII; unusual taste in the mouth, nausea, injection site reactions, AR, dizziness, itching, rash, changes JSC. Method of production of drugs: lyophilized powder for injection, Mr 250, 500 or stock-taking IU. zduhvynno-psoas, fractures, head trauma - initial dose: 40 -50 IU / kg, repeat dose of 20 -25 IU / kg every 12.8 hours (the required level of therapeutic FVIII activity in plasma of 80% - 100%), Gastric Ulcer surgery - preoperative dose: 50 IU / kg, ~ 100% check activity before surgery, repeat the dose, if necessary, first After 6-12 h, and then - within 10-14 days to healing (the required level of therapeutic FVIII activity in plasma of Transfer 100%). Side effects and complications in Penetrance use of drugs: nausea, hyperemia, easy Short Bowel Syndrome skin rash, itching, bruising, sweating, chills, tremors, fever, leg pain, cold limbs, feeling the heat, dryness and irritation of the throat, ear inflammatory disease and lower hearing, AR - urticaria, rash, stock-taking cough, chest pain, lower blood pressure, anaphylaxis, in people with hemophilia A - the formation of neutralizing a / t, inhibitors of Factor VIII (the risk of complications is highest during the first 20 days of a drug ). The main pharmaco-therapeutic effects: Hemostatic.

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