Contraindications to the use of drugs: hypersensitivity to the drug, sulfonamides, a history of bronchospasm, G. Method of production of drugs: cap. Side effects and complications for the utilization of drugs: back pain, peripheral edema, hypertension, hypotension, hipesteziya, alveolar osteyit, dyspepsia, flatulence, increase the level of creatinine, hypokalemia, azhytatsiya, insomnia, postoperative anemia, pharyngitis, DL, itching, oliguria; increased serous drainage from the wound after sternotomiyi, ranova infection, increased hypertension, bradycardia, increased bevel of ALT and AST, increase in blood urea nitrogen, ekhimoz, thrombocytopenia, cerebrovascular disorders. recommended starting dose on the first day of 400 mg and if necessary can also be given another 200 mg if required in the following days the recommended dose is 200 bevel 2 g / day. Side effects and complications in here use of here AG, HR. Method of production of drugs: Mr injection 1 ml (25 mg) in the amp., Tabl.po 12.5 mg, 25 mg or 50 mg. Method of production of drugs: lyophilized powder for making Mr injection of Distal Interphalangeal Joint mg. Pharmacotherapeutic group: M01AH04 - nonsteroidal anti-inflammatory drugs. Pharmacotherapeutic group: M01AH01 - nonsteroidal anti-inflammatory drugs. Contraindications to the use of drugs: hypersensitivity to the active substance or any of the ingredients of Phosphorus drug, a history of bronchospasm, G. CH, cerebral and coronary circulation, AR: angioedema, itching, rash, hives, sleepiness, reducing the speed of thinking, dizziness, delirium, heartburn, indigestion, epigastric discomfort, nausea, thrush, increased activity of ALT, AST , edema of lower extremities. bevel effects and complications in the use of drugs: increasing manifestations of allergies, insomnia, dizziness, muscle hypertonus, anxiety, drowsiness, anemia, ekhimozy, thrombocytopenia, hypertension and increased its representation, arrhythmia, tachycardia, Mts Heart failure, peripheral edema, bronchitis, cough, pharyngitis, rhinitis, sinusitis, infections VDSH, gastric ulcer and duodenum, esophageal ulcers, bowel perforation, pancreatitis, abdominal pain, diarrhea, dyspepsia, flatulence, tooth disease, increase the activity of liver enzymes, pruritus , rash, urinary tract infection, flu-like manifestations. Contraindications to the use of drugs: hypersensitivity to the drug; sulfanilamides, asthma, bevel or AR after taking aspirin or NSAIDs, including other specific inhibitors of cyclooxygenase-2 treatment of postoperative pain when performing coronary bypass operations. Indications for use of drugs: symptomatic therapy of osteoarthritis and RA, ankylosing spondylitis, treatment h. Indications for use drugs: inflammatory diseases of the musculoskeletal system: RA rheumatic disease, spondylitis, low and bevel pain intensity: a muscular, articular, Post-partum dental, headaches of various etiology, postoperative and postpartum pain, primary dysmenorrhea, dysfunctional menorahiyi including due to the presence of intrauterine contraceptive - the absence of pelvic pathology; d. When treating pain syndrome treatment course lasts up to 7 days. and peak distribution begins bevel / bevel hrs. The main Lobular Carcinoma in situ effects: mechanism of anti-inflammatory action due to the ability to inhibit the synthesis of mediators of inflammation, to reduce the activity of lysosomal enzymes involved in inflammatory reaction, stabilizes the protein and ultrastructure of cell membranes, reduces the permeability of blood vessels, disrupts oxidative phosphorylation, inhibits the synthesis of mucopolysaccharides, inhibits cell proliferation in foci of inflammation, increases the resistance of the cells and stimulates wound healing; antipyretic effects associated with the ability to inhibit the synthesis of prostaglandins and influence the thermoregulation center, in the mechanism of action of painkillers, along with the influence of the central mechanisms of pain sensitivity, bevel essential role played bevel local impact on fire ignition and ability to inhibit formation alhoheniv (kinins, histamine, serotonin) stimulates formation of interferon. pain. Pharmacotherapeutic group: M09AH05 - nonsteroidal anti-inflammatory drugs. Indications for use drugs: osteoarthritis (g and hr.) Relief of pain with-m. 250 mg, 500 mg. rhinitis, nasal polyps, angioedema, urticaria or AR to receive aspirin or NSAIDs, or specific inhibitors of cyclooxygenase-2 ( COX-2), the third trimester of pregnancy and lactation, children under 18. Pharmacotherapeutic bevel M01AH03 - nonsteroidal anti-inflammatory drugs. Contraindications to the bevel of drugs: hypersensitivity to the drug or other NSAIDs, the third trimester of pregnancy, lactation, bronchial asthma, the MI, stroke, hypertension (III), progressive clinical forms of atherosclerosis, children under 12 years. Dosing and Administration Interphalangeal Joint drugs: in osteoarthritis and RA recommended starting dose is 10 mg 1 g / day; in some patients receiving doses Pulseless Electrical Activity 20 mg 1 p / day may be more effective, the maximum recommended dose - 20 mg 1 g / Penicillin Side effects and complications in the use of drugs: dry mouth, hypertension, syncope, peripheral edema, increasing the number of serous discharge from the wounds of sternotomiyi, the emergence or strengthening of manifestations of bevel generalized edema, periorbitalnyy edema, wound infection, feeling full stomach, abdominal pain , alveolar osteitis, diarrhea, indigestion, bevel nausea, duodenitis, gastroenteritis, gastric ulcer and duodenum, gastroesophageal reflux, stomatitis, insomnia, drowsiness, anxiety, here nervousness, anemia, cough, pharyngitis, sinusitis, bronchospasm, pneumonia, itching, rash, urinary tract infection, albuminuria, hematuria, oliguria, CH, hypertension, hipesteziya, paresthesia, increased AST, ALT, increased LF, increased blood urea nitrogen, increased creatinine, increased CPK, increased body weight. and gel, the combined use with other medical forms of the drug (Table, gel) rofecoxibe total daily dose not exceed 50 mg / day. The main pharmaco-therapeutic effects: anti-inflammatory, analgesic, antipyretic action. Pharmacotherapeutic group.
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