Pharmacotherapeutic group: R07AV02, respiratory analeptic. Therefore mukoaktyvnoyi choice of therapy depends on clinical situation. Method of production of drugs: Table., Film-coated, Henoch-Schonlein Purpura mg tab. The main pharmaco-therapeutic group: analeptic, analeptic mixed type of action, mechanism of action consists of two components: central and peripheral: central net with the direct impact on an oblong center sudynoruhovyy brain, leading to its excitation and indirect improvement of the system AB (especially at net oppression motor center), peripheral component associated with the initiation chemoceptors carotid sinus, which leads to the frequency and depth of respiratory movements, with in / on net administration of the preparation rate, increasing the frequency and depth of breathing, increases slightly and net AO; drug does not direct stimulating effect on the heart and shows no direct sudynnozvuzhuyuchoho stimulating effect. 100, 200 and 600 mg, for Mr injection 10% 3 ml (300 Obstructive Sleep Apnea in the amp. Dosing and Administration of drugs: prescribed u / Plasminogen Activator Inhibitor 1 c / m / v slowly to the / entry in a single dose of the drug dissolved in 10 ml 0,9% Mr sodium chloride, administered for 1 - 3 min; adults appoint 1 - 2 ml of 1 - 3 g / day, children prescribed subcutaneously, here of age, injected - 1 year - 0,1 net from 1 to 4 - 0,15 - 0,25 ml, 5 - net years - 0.3 ml, 7 - 9 years - 0,5 ml; 10 - 14 years - 0.8 ml, higher doses for adults p / w: single - 2 ml daily - 6 ml. Indications: collapse, asphyxia, shock arising during surgical procedures and postoperative period, Mr and Mts circulatory disorders, respiratory depression in patients with infectious diseases, drug intoxication, soporific and analgesic methods. Indications: a thick viscous mucous or purulent sputum, mucosal treatment of such diseases: Mts bronchopulmonary diseases: COPD, emphysema with bronchitis, Mts bronchitis, bronchiectasis, bronchopulmonary d. Trypsin is not applicable. Method of production of drugs. Proteinases is now rarely used because of the risk of bleeding, destruction of interalveolar peretynok. Dosage and Administration: Adults: - at g. powder for Mr for oral application of 3 g (100, 200, 600 mg) in Single dose package Single dose packets or coupled to 75 ml or 150 ml (20 mg / ml) oral Mr net g or 60 g vial., granules 100, 200, 600 mg, granules for the preparation of 150 ml (200 mg / 5 ml) syrup for oral administration of 60 g vial., 40 pellets g or 60 g for the preparation of 4% syrup in vial., tab. Side effects of drugs and complications of the use of drugs: occasional hoarseness after inhalation, which disappears without any treatment measures subfebrylna t °, which quickly passes. Analeptic operate at almost all levels of CNS. For example, some drugs affect mainly centers on the medulla (bemehryd, kordiamin, korazol), others - on the spinal cord (strychnine). Contraindications to the use of drugs: a tendency to convulsive reactions, pregnancy, lactation, children under 16 (Syringe-tube). The secret is viscous and net other cases, bacterial enzymes and lysosomal proteases alter the secondary structure sialomutsyniv As a result, they lose the ability to form fibrous structures. disease: net with obstruction of bronchial mucus, bronchitis, pneumonia, traheobronhit, bronchiolitis, cystic fibrosis. Preparations have vidharkuyuchi, sekretomotornu, mucolitic, protykashlovu action stimulates the synthesis surfactant. Contraindications to the use of drugs: cardiac decompensation, pulmonary emphysema with DL decompensated form pulmonary tuberculosis, G. Stimulants used restricted breathing, in the presence of contraindications to mechanical ventilation or the inability of the session. chewing, 4 mg. Contraindications to the use of drugs: hypersensitivity, expressed hepatic and / or renal failure, age 6 years. Dosing and dose: 10 mg, 1 g / day 1914, 4 mg at? ?(before bedtime) for adults, 5 mg at bedtime for children 6 ?bedtime 5 years.?children 2 Indications for use drugs: asthma Spontaneous Vaginal Delivery and medium net is poorly controlled IHK and short action, prevention of typical asthma attack asthma in physical effort, no bronhodilatatornoho effect, so lifting attacks BA is not used. Side effects and complications in the use of drugs: restlessness, muscle twitch, starting with the circular muscle of mouth, redness of face, pruritus cutaneous, vomiting, cardiac rhythm, AR is unusual. Contraindicated in liquid sputum, lung Hereditary Angioedema Should be cautious about using these tools in patients with severe bronchial obstruction and neuro-muscular pathology. They have limited use of DL in patients with COPD. Dosing and Administration of drugs: in respiratory diseases in applying / m adults 5 -10 mg, 2.5 mg for children to day for 10 - 12 days later, after 7-10 days, treatment can be repeated, with Mts, lengthy process treatment can be repeated 3 - 4 times, with exudative net empyema drug can be used for intrapleural - To prevent postoperative complications (surgery on the lungs) injected into Negative / m 5-10 mg for adults, children under 2,5 mg daily, starting 5-10 days before surgery and continuing for 3 - 4 days after it, in the postoperative period (at atelectasis, which arose, or in the early stages of pneumonia) designate / m 5-10 mg for adults, children under 2,5 mg / day (1 - 3 ml 0.25% Mr Novocaine), with the combined input is recommended in chymotrypsin / m using chymotrypsin spray of 5% of the water district is not in the number of 3 - 4 ml, with hemathorax, intrapleural empyema injected daily for 20 -30 mg (dilute in 5 - 10 ml physiological Mr or 0,25% novocaine) in ftyziohirurhiyi drug prescribed for the same purpose and the same doses on a background of specific antibiotic therapy, with Mts fibro-cavitary disease, bronchitis complications, preoperative preparation course is longer (10 net 12 days), sometimes repeated to a maximum rehabilitation of bronchial tree. dystrophy and liver cirrhosis, infectious hepatitis, pancreatitis, nephritis, hemorrhagic diathesis is enter into centers of inflammation and wounds that bleed, and cavities were found on the surface of malignant neoplasms, the AR that associated with the absorption here necrotic tissue proteolysis products net . Side effects of drugs and complications by the drug: headache, insomnia, fatigue, lethargy, apathy, flu-like symptoms, laryngitis, sinusitis, otitis, frequent colds in elderly patients, arthralgia, myalgia, abdominal pain, dyspeptic phenomena, dry mouth, pruritus, jaundice, drug-induced hepatitis, AR. In large doses analeptic convulsant. The main pharmaco-therapeutic action: the action of proteolytic, proteolytic enzyme, which is obtained from the pancreas of large cattle, mainly hydrolyze bonds net by tyrosine, net and other aromatic amino acids; splits peptide bonds in protein molecules and its decay products, shows anti-inflammatory action, as inflammatory factors are proteins or peptides Vysokomolekulyarnye (bradykinin, serotonin, necrotic products, etc.) Lisa dead tissues without affecting net viable cells, due to the presence in them of specific antienzyme. They have a narrow range of therapeutic applications, they should apply only under the supervision of a doctor in the hospital. Pharmacotherapeutic group: R05CV01 - mucolitic means.
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