Broad-spectrum antibiotic. Drug is prescribed orally 4 times a day to prevent the seasonal exacerbation-tions rheumatism, chronic strep pharyngitis, otitis media, infections of the mouth. Is highly toxic bleep . Amoxicillin side effects: nausea, vomiting, glossitis, stomatitis, diarrhea, rash, hypersensitivity reactions (urticaria, angioedema, anaphylaxis, hemolytic anemia, interstitial nephritis), at higher doses or renal failure - the convulsive reaction. Strains of staphylococci resistant to these drugs, called metitsil-linrezistentnymi staphylococci. Amoxicillin is better absorbed in the intestine. In high doses or in severe renal non-sufficiency benzylpenicillin may cause encephalopathy, convulsions, coma. Aminopenicillins - amoxicillin, ampicillin operate on the same exciter-Teli that benzylpenicillin (except for the pale treponema), as well as a number of Gram-negative pathogens - Salmonella, shigella, E. Imipenem is inactivated degidropeptidazoy kidneys, so bleep is prescribed together with an inhibitor of this enzyme - cilastatin; there is a combined medication tienam. The spectrum of antimicrobial action similar bleep penicillin phenoxymethylpenicillin, but is less effective. Possible hemolytic anemia, interstitial nephritis, neutropenia, thrombocytopenia. Operates mainly on gram-positive bacteria, including staphylococci, penicillinase producing. Benzylpenicillin in general little toxic but can cause hyper-sensitivity reactions - urticaria, pyrexia, pain joint pain, rashes, angioedema, anaphylactic shock. In this group of penicillins, isolated aminopenicillins, karboksipenitsil-Lina, ureidopenitsilliny. Drugs in this group - meropenem and imipenem - antibiotics action spectrum. Virtually ineffective against a pale treponema. bleep in severe staphylococcal and streptococcal infections Severe Combined Immunodeficiency pneumonia, brain abscess, pulmonary, meningitis, peritonitis, osteomyelitis, streptococcal endocarditis); injected ka-pelno. Similar properties has teikoplanin. Violates the synthesis of peptidoglycan: Institute lipidpirofosfatazu inhibits and prevents restoration of activity (dephosphorylation) pyrophosphate bleep Chica S55 after the implementation here its transport function. Cycloserine - a structural analogue Dalanina 1) inhibits alaninratsemazu and disrupts the formation of Dalanina Lalanina, 2) inhibits dipeptidsintetazu and disrupts the formation of the dipeptide Dala - Dala, 3) violates the accession Dala - Dala a tripeptide which is connected to Natsetilmuramatom. Violates the synthesis of peptidoglycan. The first drug of this group was methicillin. Side effects of cephalosporins: an allergic reaction is possible nephro-toxicity, especially when using a drug generation. Unlike benzylpenicillin resistant to HC1 gastric juice. Unlike aminopenicillins act on sineg-Noyna wand. IV generation cephalosporins act on gram-positive and Gram-tional bacteria, are effective Save Our Souls Pseudomonas coli and Proteus. coli. Effect on staphylococci, stable curves to benzylpenicillin. Amoxiclav (augmentin) is effective against cocci, Haemophilus paloch-ki, Escherichia coli, Shigella, Legionella, Salmonella, Proteus, Klebsiella, anaerobic pathogens, including Bacteroides fragilis and other microorganisms. Ureidopenitsilliny - azlocillin, piperacillin - broad-spectrum antibiotics. Therefore, aminopenicillins advisable to appoint, together Photodynamic Therapy inhibitors betalakta Maze - clavulanic acid or sulbactam. Sequential Multiple Analysis drugs are on the spectrum of antimicrobial action similar to penicillin, but less effective. Aminopenicillins no effect on the microorganisms that produce betalaktamazy (including penicillinase). Currently applied Ute cloxacillin, dikloksatsillin, bleep oxacillin. Effective against Clostridium difficile.
No comments:
Post a Comment